Bio-antimutagen Detection Method with Wing Spot Test by Drosophila melanogaster.
نویسندگان
چکیده
منابع مشابه
Genotoxicity of lapachol evaluated by wing spot test of Drosophila melanogaster
This study investigated the genotoxicity of Lapachol (LAP) evaluated by wing spot test of Drosophila melanogaster in the descendants from standard (ST) and high bioactivation (HB) crosses. This assay detects the loss of heterozygosity of marker genes expressed phenotypically on the fly's wings. Drosophila has extensive genetic homology to mammals, which makes it a suitable model organism for ge...
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Halogenated aliphatic compounds were evaluated for toxic and genotoxic effects in the somatic mutation and recombination test employing Drosophila melanogaster. The tested chemicals included chlorinated, brominated and iodinated; mono-, di- and tri-substituted; saturated and unsaturated alkanes: 1,2-dibromoethane, 1-bromo-2-chloroethane, 1-iodopropane, 2,3-dichloropropene, 3-bromo-1-propene, ep...
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The wing somatic mutation and recombination test (SMART) using Drosophila melanogaster was employed to determine the recombinagenic and mutagenic activity of four chemicals in an in vivo eukaryotic system. Two different crosses involving the wing cell markers mwh and flr(3) were used: the standard cross and a high bioactivation cross. The high bioactivation cross is characterized by a high cons...
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LARGE proportion of the X chromosome deficiencies maintained A in stock at this laboratory are balanced over In(~)dl-qg, y Hw. When such deficiencies were examined cytologically, it was frequently noticed, especially when the chromosomes were unpaired, that there was some departure from the normal salivary gland chromosome banding of the tip region of the X carrying Hw. Since such material was ...
متن کاملSelection on wing allometry in Drosophila melanogaster.
Five bivariate distributions of wing dimensions of Drosophila melanogaster were measured, in flies 1) subjected to four defined environmental regimes during development, 2) taken directly from nature in seven U.S. states, 3) selected in ten populations for change in wing form, and 4) sampled from 21 long inbred wild-type lines. Environmental stresses during development altered both wing size an...
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ژورنال
عنوان ژورنال: Eisei kagaku
سال: 1994
ISSN: 0013-273X
DOI: 10.1248/jhs1956.40.498